Herpes simplex - Herpes Simple
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Herpes simple no beizo.
Herpes Simple (Herpes simplex) ― A infección por herpes simple nos dedos é máis común nos nenos pequenos que nos adultos.
References
A infección por HSV-1 progresa a través da infección primaria das células epiteliais, seguida da latencia, principalmente nas neuronas, e a reactivación. O HSV-1 adoita causar erupcións vesiculares iniciais e recorrentes, principalmente na boca e na mucosa xenital. As súas manifestacións van desde o herpes orolabial ata varias condicións como foliculite herpética, infeccións cutáneas, afectación ocular e casos graves como a encefalite herpética. A terapia antiviral axuda a xestionar a infección por HSV.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 1 (HSV-1) is a member of the Alphaherpesviridae subfamily. Its structure is composed of linear dsDNA, an icosahedral capsid that is 100 to 110 nm in diameter, with a spikey envelope. In general, the pathogenesis of HSV-1 infection follows a cycle of primary infection of epithelial cells, latency primarily in neurons, and reactivation. HSV-1 is responsible for establishing primary and recurrent vesicular eruptions, primarily in the orolabial and genital mucosa. HSV-1 infection has a wide variety of presentations, including orolabial herpes, herpetic sycosis (HSV folliculitis), herpes gladiatorum, herpetic whitlow, ocular HSV infection, herpes encephalitis, Kaposi varicelliform eruption (eczema herpeticum), and severe or chronic HSV infection. Antiviral therapy limits the course of HSV infection.
Herpes simplex virus type 2 (HSV-2) é unha infección xeneralizada, que afecta ao redor do 22% dos adultos de 12 ou máis anos, con un total de 45 millóns de adultos nos Estados Unidos. Aínda que o HSV-1 normalmente causa feridas orais, tamén pode provocar lesións xenitais. Non obstante, cando os pacientes teñen lesións xenitais, o HSV-2 adoita ser a principal preocupación. Os síntomas dos brotes de HSV-2 adoitan ser vagos, como coceira e irritación xenital, que poden atrasar o diagnóstico e o tratamento. Este atraso pode producir unha maior transmisión a persoas non infectadas.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus type 2 (HSV-2) continues to be a common infection, affecting approximately 22% of adults ages 12 and older, representing 45 million adults in the United States alone. While HSV-1 often affects the perioral region and can be known to cause genital lesions, HSV-2 is more commonly the consideration when patients present with genital lesions. Despite this, most outbreaks of the infection will present with nonspecific symptoms such as genital itching, irritation, and excoriations, which may cause diagnosis and treatment to be delayed. As a result, further exposure to uninfected individuals may occur.
Herpes simplex virus (HSV) adoita causar infeccións como o herpes xenital e o herpes labial en adolescentes e adultos. Cando o HSV infecta a un bebé nas primeiras 4-6 semanas de vida, pode provocar unha enfermidade grave con graves consecuencias. O diagnóstico rápido da infección neonatal por HSV é fundamental para evitar que a enfermidade empeore, evitando problemas neurolóxicos (incluso a morte) .
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
Herpes simplex virus (HSV), a member of the Herpesviridae family, is a well-known cause of infections including genital herpes and herpes labialis in the adolescent and adult population. Transmission of HSV infection to an infant during the first 4-6 weeks of life can lead to devastating disease with the potential for poor outcomes. Early diagnosis is imperative when evaluating neonatal HSV infection in order to prevent further disease progression, neurological complications, and even death.
A Herpes simplex infección é moi común e pódese transmitir das mulleres embarazadas aos seus bebés. Este virus pode causar graves problemas de saúde ou incluso a morte en recentemente nados. Aínda que é raro durante o propio embarazo, moitas veces ocorre durante o parto. O risco é maior se a nai se infecta nas últimas etapas do embarazo. Non obstante, este risco pódese reducir mediante o uso de medicamentos antivirais ou optando por unha cesárea en determinadas situacións.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Infection with herpes simplex is one of the most common sexually transmitted infections. Because the infection is common in women of reproductive age it can be contracted and transmitted to the fetus during pregnancy and the newborn. Herpes simplex virus is an important cause of neonatal infection, which can lead to death or long-term disabilities. Rarely in the uterus, it occurs frequently during the transmission delivery. The greatest risk of transmission to the fetus and the newborn occurs in case of an initial maternal infection contracted in the second half of pregnancy. The risk of transmission of maternal-fetal-neonatal herpes simplex can be decreased by performing a treatment with antiviral drugs or resorting to a caesarean section in some specific cases.
Herpes simplex virus (HSV) tipos 1 e 2 infectan a moitas persoas en todo o mundo. Normalmente, o virus permanece quieto nas células nerviosas despois de infectar a pel, pero pode reactivarse máis tarde, causando herpes labial. Ás veces, leva a problemas graves como infeccións oculares, inflamación do cerebro ou condicións perigosas en recentemente nados e persoas con sistemas inmunes débiles. Aínda que os medicamentos actuais axudan a controlar as infeccións, o risco de resistencia aos medicamentos e os efectos secundarios seguen sendo preocupantes. Necesitamos novos medicamentos para atacar mellor o virus.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Infection with herpes simplex virus (HSV) types 1 and 2 is ubiquitous in the human population. Most commonly, virus replication is limited to the epithelia and establishes latency in enervating sensory neurons, reactivating periodically to produce localized recurrent lesions. However, these viruses can also cause severe disease such as recurrent keratitis leading potentially to blindness, as well as encephalitis, and systemic disease in neonates and immunocompromised patients. Although antiviral therapy has allowed continual and substantial improvement in the management of both primary and recurrent infections, resistance to currently available drugs and long-term toxicity pose a current and future threat that should be addressed through the development of new antiviral compounds directed against new targets.
Hai dous tipos de virus herpes simple (herpes simplex) , o tipo 1 (HSV-1) e o tipo 2 (HSV-2). O HSV-1 causa máis comúnmente infeccións arredor da boca mentres que o HSV-2 causa máis comúnmente infeccións xenitais. Transmítense por contacto directo co individuo infectado. O herpes xenital clasifícase como unha infección de transmisión sexual. Pódese transmitir a un bebé durante o parto. Despois da infección, os virus son transportados polos nervios sensoriais ata os corpos das células nerviosas, onde residen durante toda a vida. As causas de recorrencia poden incluír: diminución da función inmune, estrés e exposición á luz solar.
Na maioría dos casos, os medicamentos antivirais só se toman cando os síntomas son graves. Os medicamentos antivirais diarios pódense receitar a alguén que teña unha infección moi frecuente. Non hai vacina dispoñible e a vacina contra o herpes zóster non prevén o herpes simple. Os tratamentos con medicamentos antivirais como aciclovir ou valaciclovir poden diminuír a gravidade dos síntomas.
As taxas mundiais de HSV-1 ou HSV-2 están entre o 60% e o 95% en adultos. O HSV-1 adoita estar infectado durante a infancia. Estímase que 536 millóns de persoas en todo o mundo (o 16% da poboación) estaban infectadas con HSV-2 en 2003, con maiores taxas entre as mulleres e os do mundo en desenvolvemento. A maioría das persoas con HSV-2 non se dan conta de que están infectadas.
○ Tratamento - Medicamentos OTC
Evite calquera contacto físico, como bicar a un neno, mentres as burbullas estean presentes, xa que o contacto pode transmitir a infección a outras persoas. Debes descansar sen beber alcohol.
#Acyclovir cream